Mattel, which makes Barbie, American Girl and Fisher Price products, among others, said the positions amount to 3 percent of its worldwide work force and will reduce its professional and management staff by 8 percent.
The company said the cuts will come from a combination of layoffs, attrition and retirements and will not affect holiday toy production.
Mattel did not break down the numbers by region but said about 170 positions were cut at its El Segundo, Calif. headquarters. Some 70 job cuts are at the company's Fisher Price unit, which has a total staff of 900.
"We had our best year last year. ... However, we're not immune to the unbelievable, unprecedented rise in the cost of manufacturing, the recessionary trends and the slowing economy," Fisher Price spokeswoman Brenda Andolina said from the unit's headquarters in the Buffalo, N.Y., suburb of East Aurora.
There were also an undisclosed number of job cuts at Mattel's American Girl division, as well as international sales and marketing offices globally.