Those are just some of the findings from Ernst & Young's global biotechnology report 2009, its 23rd annual look at the industry.
The report by Ernst & Young says U.S. profit for the industry totaled $800 million. Globally, the still-developing industry lost $1.4 billion.
But the report also says young biotechnology companies also are seeing less money from investors because of the financial crisis.
Stock market declines have cut public investors' appetite for risk — and biotech has always been relatively risky.